Conolidine’s analgesic outcomes stem from its conversation with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors from the central nervous system, conolidine modulates alternate molecular targets. A Science Improvements review uncovered that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabilit... https://conolidintoreplacetraditi72592.blogoxo.com/39186315/alternative-natural-pain-relief-to-replace-traditional-painkillers-an-overview