In this article, we demonstrate that conolidine, a pure analgesic alkaloid Employed in classic Chinese medicine, targets ACKR3, thereby delivering supplemental evidence of the correlation involving ACKR3 and discomfort modulation and opening choice therapeutic avenues with the therapy of Long-term suffering. The first asymmetric overall synthesis of conolidine was https://mannersk403qbn5.life-wiki.com/user