The term "cfDNA methylation" refers to the epigenetic modification that takes place in cfDNA. These small DNA fragments circulate in the bloodstream, primarily tilizing cfdna methylation for early cancetracking of disease progressioncovalent addition of a methyl group to cytosine residues, particularly in regions rich in CpG dinucleotides, termed CpG islands. This modification can pro... https://www.cd-genomics.com/epigenetics/resource-cfdna-methylation-sequencing-methods-database-function.html